How is it going to be played?
As a boxing analyst, (I have analyzed lots of fights that seemed to agree with my theories and expectations) I will point out the difference between the two, starting off with height. Margarito is taller than Pacquiao, as the fight goes along, I know it wouldn't be a factor. As I've seen Margarito's fights, he is the type who bends his head towards his chest, and is more of a slugger than a boxer. I can compare Margarito to Oscar de la Hoya, but in terms of skills, a prime De la Hoya, to me, is better. Pacquiao will be lunging in and out like he always does, which will help to his advantage. Pacquiao has better boxing ability compared to Margarito. I can picture, Margarito chasing on Pacquiao, as he is turning on angles, going in and out. In terms of speed, Pacquiao is on the clear advantage, hands down. The fight will seem to follow the same pattern of the De la Hoya-Pacquiao fight, as Manny will be utilizing his footwork, trying to turn Margarito, who is a slugger. In terms of power, I believe, Pacquiao should not take a gamble, and trade with Margarito. I suggest that he should be contented hammering him, with boxing. Margarito's uppercuts are lethal, but Pacquiao's "in and out" will neutralize that. Pacquiao will have an advantage of stance, as he is a southpaw. I expect, lots of left straights from Manny in this fight.
My Prediction
Pacquiao will win by knock out! An early knock down, is possible, perhaps in the third to fifth rounds. The knock out will come at rounds eight to ten. It will never go past round 10. Pacquiao will use some boxing in the early rounds, with some flashes of power, here and there. As the fight progresses, I can see Margarito slowing considerably on rounds six onwards. Pacquiao will take advantage on that reduction of speed, and will start hammering and trading shots at that point. Margarito will be on the defensive on the later rounds, and I can see Pacquiao chasing him, and pouring lots of punches. I say this, it's because, Margarito isn't much of a fast fighter, so I can see Pacquiao hurting Margarito early. As Margarito is being pummeled continuously, he won't be the same, that's why I said he'd slow down. All in all, the key for Pacquiao to winning the fight is, boxing ability, power, accuracy, foot work, angles, and speed. As for Margarito, if he could learn to counter effectively, it would make Pacquiao more hesitant, and would work to his advantage. Margarito should fight tall, and use that solid left jab of his. He should not expect a slug fest from Manny, because it's not going to happen, so the best way is for him to box effectively. The first who makes the mistake, will be the first to lose, that is why, patience is a virtue, especially in boxing.
It's Significance
If Manny Pacquiao will win this fight, it would make him an eight division world champion, putting him further to the top, as the first one to do it. The second fighter to win a championship in different divisions, only won at six weight classes, therefore, an eight division champion is definitely unheard of. It will cement his status as part of the Hall of fame, and an all time great. If Margarito will pull out an impressive upset, it will garner him the status as part of the elite rankings in his division, and pound for pound. If Margarito will win this, I think Floyd Mayweather Jr. will be top one, and Margarito will be top two respectively.
Final Thoughts
Again, all these are opinions, and anything can happen in the boxing ring. Manny Pacquiao and Antonio Margarito are great fighters, and I expect a great fight from them that people will talk for ages. HBO boxing has been so great for the sport, I wish they would continue to do what they do, in bringing excitement in major boxing events. I will leave you all with some words to ponder, as I say, "A challenge, is a food for champions, without them, there will be no champions."
Trivia
Antonio Margarito was banned for years due to illegal hand wrapping with a solution of "Plaster of Paris" after his fight with Sugar Shane Mosley.
Antonio Margarito has the same boxing nickname as I am, as he is the "Tijuana Tornado", my nickname is "Tornado".